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RESVANTAGE SUPPLEMENT FOR DOGS is approved by THE CANINE CANCER FOUNDATION made in the USA
A PRECISE SYNERGISTIC BLEND CUSTOM FORMULATED FROM NATURAL SOURCES that include Omega 3 fatty acids, cell protecting antioxidants, amino acids, trace minerals and vitamins all working together to address a wide range of canine health needs and to promote:
Resveratrol – A naturally occurring polyphenol demonstrating diverse health benefits including antioxidant, anti-inflammatory, cardio protective and neuro protective properties. A number of preclinical findings suggest resveratrol having high therapeutic potential for cancer prevention and treatment.* It helps support normal metabolic function and been shown in studies to counter insulin resistance.
*National Cancer Institute Fact Sheet "What is resveratrol and how does it prevent cancer?"
Atlantic Kelp – Rich in vitamins, trace minerals and amino acids which are essential for complete nutritional support. Sea kelp is also a natural source of iodine beneficial for thyroid and glandular health and it improves digestion and reduces stress.
Flaxseed Oil – An excellent source of Omega-3 fatty acids are critically important for neuromuscular development, skin health, coat quality and are used for inflammatory skin diseases and infections, arthritis and flea and food allergies. Omega-3 fatty acids reduce triglycerides and cholesterol and help prevent blood clots.
Lecithin – A sustainer to the nervous system and brain promoting alertness and steady nerves. Lecithin emulsifies fat, improves digestion of fats, and helps remove fatty liver deposits for a healthier liver and improved metabolic process.
Ingredient Source: All the ingredients in Resvantage Canine® are naturally occurring. Resveratrol is found in more than 70 different plant varieties including grapes, peanuts, pomegranates, blueberries, pines and Giant Knotweed. Resvantage® sources its trans-resveratrol from the Knotweed plant; Botanical name - Polygonum Cuspidatum. This is the same source of pharmaceutical grade resveratrol used in studies conducted by the NIH and other medical research institutions and universities.
Capsule Integrity: Resvantage Canine® is manufactured to cGMP* standards and a rigorous quality assurance program. It is lab tested during all phases of the process insuring that the active compounds are free of heavy metal toxicity and microbiological contaminants.
RESVANTAGE CANINE® is Laboratory Tested and then encapsulated in an oxygen-free, nitrogen-rich environment by the Capsugel® division of Pfizer utilizing their exclusive patented Licaps® process. This helps prevent oxidation and ensures that each capsule retains its potency.
Administration: Resvantage Canine® capsules are intended to be taken orally.
Suggested Use: Give dogs 1 capsule daily for every 30 lbs. If giving more than one capsule daily, divide between AM and PM. Suggested dose may be increased safely for managing acute/severe conditions such as cancer or diabetes.
Safety/Resveratrol: Resveratrol is well tolerated and safe for long-term daily use. There are no known side effects or contra-indications associated with resveratrol supplementation.
Precautions: Resvantage Canine® may reduce the need for medications for the treatment of inflammation, insulin resistance, cardiovascular or other diseases. If the dog is undergoing treatment for these, monitor and re-establish appropriate levels of medication.
Warnings: Not for puppies less than six (6) months old. Do not give to pregnant or nursing dogs or those intended to be bred for a period of 3 months prior to insemination. Do not give to dogs with an established sensitivity to iodine.
Storage: Store at room temperature, between 59°-86° F (15°-30° C). Brief periods of up to 104° F (40° C) are permitted.
How Supplied: Carton containing 30 liquid-filled capsules.
Resveratrol is a natural compound produced by certain plants on various stimuli. In recent years, extensive research on resveratrol has been carried out, demonstrating its capacity to prevent a wide variety of conditions, including cardiovascular diseases and cancer, and to control fungal, bacterial and viral infections. In the present review, we summarize the current knowledge of the activity of resveratrol against viral infection and describe the possible molecular pathways through which resveratrol exerts its antiviral activity.
Resveratrol is a potent polyphenolic compound that is being extensively studied in the amelioration of viral infections both in vitro and in vivo. Its antioxidant effect is mainly elicited through inhibition of important gene pathways like the NF-κβ pathway, while its antiviral effects are associated with inhibitions of viral replication, protein synthesis, gene expression, and nucleic acid synthesis. Although the beneficial roles of resveratrol in several viral diseases have been well documented, a few adverse effects have been reported as well. This review highlights the antiviral mechanisms of resveratrol in human and animal viral infections and how some of these effects are associated with the antioxidant properties of the compound.
Resveratrol is a non flavonoid polyphenol compound present in many plants and fruits and, at especially high concentrations, in the grape berries of Vitis vinifera. This compound has a strong bioactivity and its cytoprotective action has been demonstrated, however at high concentrations the drug exhibits also an effective anti-proliferative action. We recently showed its ability to abolish the effects of oxidative stress in cultured cells. In this work we assayed the bioactivity of resveratrol as antiproliferative and antiviral drug in cultured fibroblasts. Studies by other Authors showed that this natural compound inhibits the proliferation of different viruses such as herpes simplex, varicella-zoster and influenza A. The results presented here show an evident toxic activity of the drug at high concentrations, on the other hand at sub-cytotoxic concentrations, resveratrol can effectively inhibit the synthesis of polyomavirus DNA. A possible interpretation is that, due to the damage caused by resveratrol to the plasma membrane, the transfer of the virus from the endoplasmic reticulum to the nucleus, may be hindered thus inhibiting the production of viral DNA.
The mouse fibroblast line 3T6 and the human tumor line HL60 were used throughout the work. Cell viability and vital cell count were assessed respectively, by the MTT assay and Trypan Blue staining. Cytotoxic properties and evaluation of viral DNA production by agarose gel electrophoresis were performed according to standard protocols.
Our results show a clear dose dependent both cytotoxic and antiviral effect of resveratrol respectively at high and low concentrations. The cytotoxic action is exerted towards a stabilized cell-line (3T6) as well as a tumor-line (HL60). Furthermore the antiviral action is evident after the phase of virion entry, therefore data suggest that the drug acts during the synthesis of the viral progeny DNA.
Resveratrol is cytotoxic and inhibits, in a dose dependent fashion, the synthesis of polyomavirus DNA in the infected cell. Furthermore, this inhibition is observed at non cytotoxic concentrations of the drug. Our data imply that cyto-toxicity may be attributed to the membrane damage caused by the drug and that the transfer of polyomavirus from the endoplasmic reticulum to the cytoplasm may be hindered. In conclusion, the cytotoxic and antiviral properties of resveratrol make it a potential candidate for the clinical control of proliferative as well as viral pathologies.
This information was taken from PUBMED.GOV because there is no cure for this virus at this time but we can all help to protect ourselves and I personally believe this is the best start we can do along with washing your hands for 20 seconds and using sanitizing gel and wipes.
"an ounce of prevention is a pound of cure"